Bcolz
Bcolz is a Python package providing high-performance numpy style access to data stored in arrays or tables backed by either memory or disk.
Pandas
Pandas is a Python library for data manipulation and analysis, e.g
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I haven t played around with it recently but i think bcolz is more flexible here in terms of mixing dtypes but doesn t give you all the pandas dataframe conveniences obviously from question Sparse versions of Pandas DataFrame |