GNOME is an open source desktop environment
KDE is a powerful graphical desktop environment for Unix workstations.
"On kde aptana ran perfectly quicker than on gnome at the best of times"
from question "Why is Aptana Slow on Gnome 3 and Nvidia on Mageia 2?"
"The motivation is that font size 12 under kde seems to be much larger than under gnome"
from question "Is there a way to determine if GNU Emacs 23 (or higher) is running under KDE?"